Academic publications

Claire Duvallet, Bryan D Hayes, Timothy B Erickson, Peter R Chai, Mariana Matus.
“Mapping community opioid exposure through wastewater-based epidemiology as a means to engage pharmacies in harm reduction efforts.”
Preventing Chronic Disease (2020). doi: 10.5888/pcd17.200053

Fuqing Wu, Amy Xiao, Jianbo Zhang, … Claire Duvallet … Eric J Alm.
“SARS-CoV-2 titers in wastewater foreshadow dynamics and clinical presentation of new COVID-19 cases.”
medRxiv (2020). doi: 10.1101/2020.06.15.20117747v2

Fuqing Wu, Amy Xiao, Jianbo Zhang, Xiaoqiong Gu, Wei Lin Lee, Kathryn Kauffman, William Hanage, Mariana Matus, Newsha Ghaeli, Noriko Endo, Claire Duvallet, Katya Moniz, Timothy Erickson, Peter Chai, Janelle Thompson, Eric Alm.
“SARS-CoV-2 titers in wastewater are higher than expected from clinically confirmed cases.”
mSystems (2020). doi: 10.1128/mSystems.00614-20

Claire Duvallet.
“Data detectives, self-love, and humility: a research parasite’s perspective.”
GigaScience (2020). doi: 10.1093/gigascience/giz148.

Noriko Endo, Newsha Ghaeli, Claire Duvallet, Katelyn Foppe, Timothy B Erickson, Mariana Matus, Peter R Chai.
“Rapid Assessment of Opioid Exposure and Treatment in Cities Through Robotic Collection and Chemical Analysis of Wastewater.”
Journal of Medical Toxicology (2020) doi: 10.1007/s13181-019-00756-5.

Ethan D Evans, Claire Duvallet, Nathaniel D Chu, Michael K Oberst, Michael A Murphy, Isaac Rockafellow, David Sontag, Eric J Alm.
“Predicting human health from biofluid-based metabolomics using machine learning.”
medRxiv (2020) doi: 10.1101/2020.01.29.20019471.

Mariana Matus, Claire Duvallet, Newsha Ghaeli, Melissa Kido Soule, Krista Longnecker, Ilana Brito, Carlo Ratti, Elizabeth B. Kujawinski, Eric Alm.
“Untargeted detection of human health and activity markers in residential wastewater through microbiome sequencing and metabolomics.”
bioRxiv (2019) doi: 10.1101/728022.

Claire Duvallet, Caroline Zellmer, Pratik Panchal, Shrish Budree, Madji Osman, and Eric Alm.
“Framework for rational donor selection in fecal microbiota transplant clinical trials.”
PLoS ONE (2019) doi: 10.1371/journal.pone.0222881.
Associated github: cduvallet/donor-selection

Evan Bolyen, Jai Ram Rideout, Matthew R. Dillon, Nicholas A. Bokulich … Claire Duvallet … Rob Knight, Greg Caporaso.
“Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2.”
Nature Biotechnology (2019). doi: 10.1038/s41587-019-0209-9.

Chengzhen Dai, Claire Duvallet, An Ni Zhang, Mariana Matus, Newsha Ghaeli, Shinkyu Park, Noriko Endo, Siavash Isazadeh, Kazi Jamil, Carlo Ratti, and Eric Alm.
“Multi-site sampling and risk prioritization reveals the public health relevance of antibiotic resistance genes found in sewage environments.”
bioRxiv (2019). doi: 10.1101/562496.

Claire Duvallet, Kara Larson, Scott Snapper, Sonia Iosim, Ann Lee, Katherine Freer, Kara May, Eric Alm, and Rachel Rosen.
“Aerodigestive sampling reveals altered microbial exchange between lung, oropharyngeal, and gastric microbiomes in children with impaired swallow function.”
PLOS ONE (2019). doi: 10.1371/journal.pone.0216453.
Associated github: cduvallet/aspiration-analysis-public

Keegan Korthauer*, Patrick K Kimes*, Claire Duvallet^, Alejandro Reyes^, Ayshwarya Subramanian^, Mingxiang Teng, Chinmay Shukla, Eric J Alm, and Stephanie C Hicks.
“A practical guide to methods controlling false discoveries in computational biology.”
Genome Biology (2019). doi: 10.1186/s13059-019-1716-1.
Associated github: pkimes/benchmark-fdr

Thomas Gurry, HST Microbiome Consortium, Sean M Gibbons, Sean M Kearney, Ashwin Ananthakrishnan, Xiaofang Jiang, Claire Duvallet, Zain Kassam, and Eric J Alm.
“Predictability and persistence of prebiotic dietary supplementation in a healthy human cohort.”
Scientific Reports (2018) 8(1): 12699. doi: 10.1038/s41598-018-30783-1

Sean M. Gibbons, Claire Duvallet, and Eric J. Alm.
“Correcting for batch effects in case-control microbiome studies.” 
PLoS Computational Biology (2018) 14(4): e1006102. doi: 10.1371/journal.pone.0176335

Claire Duvallet. “Meta-analysis generates and prioritizes hypotheses for translational microbiome research.”
Microbial Biotechnology (2018). doi: 10.1111/1751-7915.13047

Claire Duvallet, Sean M. Gibbons, Thomas Gurry, Rafael A. Irizarry, and Eric J. Alm.
“Meta-analysis of gut microbiome studies identifies disease-specific and shared responses.” 
Nature Communications (2017). doi: 10.1038/s41467-017-01973-8
Associated github: cduvallet/microbiomeHD
Associated data: zenodo record 840333.

Scott W. Olesen, Claire Duvallet, and Eric J. Alm.
“dbOTU3: A new implementation of distribution-based OTU calling.” 
PloS ONE 12, no. 5 (2017): e0176335. doi: 10.1371/journal.pone.0176335

Non-peer reviewed academic content

[Tutorial] Claire Duvallet. “Updating your qiime2 plugin.” QIIME 2 developer docs. (2019).

[Blog post] Claire Duvallet. “Scientific discovery from a clinical study: surprises from the lung and stomach microbiomes.Nature Microbiology Community Forum. May 2019.

[Tutorial] Claire Duvallet and Mehrbod Estaki. “QIIME 2 for Experienced Microbiome Researchers.” QIIME 2 docs. (2018).

[Tutorial] Claire Duvallet. “Developing a plug-in for dummies.” QIIME 2 developer docs. (2018).

[Tutorial] Claire Duvallet. “Publishing your plugin on conda.” QIIME 2 developer docs. (2018).

[Blog post] Claire Duvallet. “Fuzzy zeros in percentile normalization method to correct for batch effects.” microBEnet: the microbiology of the Built Environment network. June 2018.

[Blog post] Claire Duvallet. “Beyond dysbiosis: disease-specific and shared microbiome responses to disease.Nature Microbiology Community Forum. December 2017.

[Dataset] Claire Duvallet, Sean M. Gibbons, Thomas Gurry, Rafael A. Irizarry, and Eric J. Alm. (2017). MicrobiomeHD: the human gut microbiome in health and disease. Zenodo. doi: 10.5281/zenodo.797943


Percentile normalization
Correcting batch effects in case-control microbiome studies. (Gibbons et al., 2018)

Distribution-based OTU calling
New implementation of Preheim et al.’s distribution-based OTU clustering algorithm. (Preheim et al., 2013; Olesen et al., 2017).

Amplicon sequencing pipeline
End-to-end pipeline to process 16S data.

Match HMDB
Script to match mz’s to the HMDB database.


[Blog post] Claire Duvallet. “A Well-Kept Secret for Finding a Job post-PhD.” MIT Graduate Admissions blog (2020).

[Blog post] Claire Duvallet. “Learning to Engage in Deep Conversations.” MIT Graduate Admissions blog (2018).

[Resource] Claire Duvallet and Monika Avello. “Graduate student support resources flowchart.” I and another student on iREFS created this flowchart to help graduate students find support at MIT.